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For maintenance treatment, direct comparisons showed the superiority of vonoprazan 20 mg/day over lansoprazole 15 mg/day (RR = 8.39, 95% CI [2.06–34.24], p = 0.001), but pooled network analysis did not demonstrate significant differences between vonoprazan and other PPIs

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To test the short-term temporal dynamics of methylation and demethylation effects, we measured the expressions of epigenetic modifying enzyme genes in BSO treatment withdrawal conditions in an in vitro mouse hepatocyte model