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The antibodies used for the western blot detection were as follows: GPX4 (ab125066), ATF4 (10835-1-AP), GSR (18257-1-AP), NRF2 (16396-1-AP), TFR (17435-1-AP), STEAP3 (Thermo Fisher PA5-20406), DMT1 (20507-1-AP), FLC (10727-1-AP), FPN1 (26601-1-AP), APP (14-9749-82), HMOX1 (10701-1-AP), LPCAT3 (67882-1-Ig), ACOT1 (ab133948), SOD3 (14316-1-AP), MMP9 (10375-2-AP), anti-4-hydroxynonenal antibody (ab46545), caspase 3 (CST: #9662), caspase 1 (CST: #2225), caspase 8 antibody (ab25901), GSDMD (ProteinTech 66387-1-Ig), and MLKL (ProteinTech 66675-1-Ig)