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micro-glutathione

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製備具有以下組成之兩(2)種pH值7.4的司馬魯肽(semaglutide)配方，其含有或不含組胺酸作為賦形劑： ‒ 司馬魯肽(semaglutide): 4.8 mg/ml ‒ 磷酸鹽：30 mM (以5.34 mg/ml磷酸氫二鈉，二水合物形式添加) ‒ 組胺酸：0或10 mM (以1.55 mg/ml L-組胺酸形式添加) ‒ 氯化鈉：6.4 mg/ml ‒ 鹽酸(HCl)，視需要添加以獲得pH值7.4 ‒ 氫氧化鈉(NaOH)，視需要添加以獲得pH值7.4 ‒ 注射用水(WFI)，作為溶劑。Prepare two (2) semaglutide formulations with pH 7.4 as the following composition, which contains or does not contain histidine as an excipient: ‒ Semaglutide: 4.8 mg/ml ‒ Phosphate: 30 mM (Added as 5.34 mg/ml disodium hydrogen phosphate, dihydrate) ‒ Histidine: 0 or 10 mM (added in the form of 1.55 mg/ml L-histidine) ‒ Sodium chloride: 6.4 mg/ml ‒ Hydrochloric acid (HCl), add as needed to obtain a pH of 7.4 ‒ Sodium hydroxide (NaOH), add as needed to obtain a pH of 7.4 ‒ Water for injection (WFI) is used as a solvent