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found hallmarks of ferroptosis in the spinal dorsal horn of BCP mice, including mitochondrial morphological changes, iron accumulation, and lipid peroxidation (46)

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We demonstrated 28 that hepatocytes expressed the cognate HMGB1 receptors TLR2, TLR3, TLR4, and TLR9 allowing for a direct response to released HMGB1 and that HMGB1 by itself can induce cell death