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It should rise from baseline if the peptide is stimulating GH effectively

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J Biol Chem (1998) 273(9):5307–14.10.1074/jbc.273.9.5307 47 RossRJLeungKCMaamraMBennettWDoyleNWatersMJet alBinding and functional studies with the growth hormone receptor antagonist, B2036-PEG (pegvisomant), reveal effects of pegylation and evidence that it binds to a receptor dimer